diff --git a/js/reactions.js b/js/reactions.js
index fd1d04f52cfe..8f8d01c738c5 100644
--- a/js/reactions.js
+++ b/js/reactions.js
@@ -1,4 +1,4 @@
-// Copyright 2020 Signal Messenger, LLC
+// Copyright 2020-2021 Signal Messenger, LLC
 // SPDX-License-Identifier: AGPL-3.0-only
 
 /* global
@@ -31,7 +31,6 @@
       const sentAt = message.get('sent_at');
       const reactionsBySource = this.filter(re => {
         const targetSenderId = ConversationController.ensureContactIds({
-          e164: re.get('targetAuthorE164'),
           uuid: re.get('targetAuthorUuid'),
         });
         const targetTimestamp = re.get('targetTimestamp');
@@ -52,7 +51,6 @@
         //   to to figure that out.
         const targetConversation = await ConversationController.getConversationForTargetMessage(
           ConversationController.ensureContactIds({
-            e164: reaction.get('targetAuthorE164'),
             uuid: reaction.get('targetAuthorUuid'),
           }),
           reaction.get('targetTimestamp')
@@ -60,7 +58,6 @@
         if (!targetConversation) {
           window.log.info(
             'No target conversation for reaction',
-            reaction.get('targetAuthorE164'),
             reaction.get('targetAuthorUuid'),
             reaction.get('targetTimestamp')
           );
@@ -91,7 +88,6 @@
 
             const mcid = contact.get('id');
             const recid = ConversationController.ensureContactIds({
-              e164: reaction.get('targetAuthorE164'),
               uuid: reaction.get('targetAuthorUuid'),
             });
             return mcid === recid;
@@ -100,7 +96,6 @@
           if (!targetMessage) {
             window.log.info(
               'No message for reaction',
-              reaction.get('targetAuthorE164'),
               reaction.get('targetAuthorUuid'),
               reaction.get('targetTimestamp')
             );
@@ -110,7 +105,6 @@
             if (reaction.get('remove')) {
               this.remove(reaction);
               const oldReaction = this.where({
-                targetAuthorE164: reaction.get('targetAuthorE164'),
                 targetAuthorUuid: reaction.get('targetAuthorUuid'),
                 targetTimestamp: reaction.get('targetTimestamp'),
                 emoji: reaction.get('emoji'),
diff --git a/protos/SignalService.proto b/protos/SignalService.proto
index 6430c730c8a8..d9a349142da4 100644
--- a/protos/SignalService.proto
+++ b/protos/SignalService.proto
@@ -209,7 +209,7 @@ message DataMessage {
   message Reaction {
     optional string emoji            = 1;
     optional bool   remove           = 2;
-    optional string targetAuthorE164 = 3;
+    reserved /* targetAuthorE164 */    3; // removed
     optional string targetAuthorUuid = 4;
     optional uint64 targetTimestamp  = 5;
   }
diff --git a/ts/background.ts b/ts/background.ts
index 03129c1b52cc..5b4248571d99 100644
--- a/ts/background.ts
+++ b/ts/background.ts
@@ -2601,7 +2601,6 @@ export async function startApp(): Promise<void> {
       const reactionModel = window.Whisper.Reactions.add({
         emoji: reaction.emoji,
         remove: reaction.remove,
-        targetAuthorE164: reaction.targetAuthorE164,
         targetAuthorUuid: reaction.targetAuthorUuid,
         targetTimestamp: reaction.targetTimestamp,
         timestamp: Date.now(),
@@ -2892,7 +2891,6 @@ export async function startApp(): Promise<void> {
       const reactionModel = window.Whisper.Reactions.add({
         emoji: reaction.emoji,
         remove: reaction.remove,
-        targetAuthorE164: reaction.targetAuthorE164,
         targetAuthorUuid: reaction.targetAuthorUuid,
         targetTimestamp: reaction.targetTimestamp,
         timestamp: Date.now(),
diff --git a/ts/textsecure.d.ts b/ts/textsecure.d.ts
index f1e1ba38d173..3a846968a5e6 100644
--- a/ts/textsecure.d.ts
+++ b/ts/textsecure.d.ts
@@ -736,7 +736,6 @@ export declare namespace DataMessageClass {
   class Reaction {
     emoji: string | null;
     remove: boolean;
-    targetAuthorE164: string | null;
     targetAuthorUuid: string | null;
     targetTimestamp: ProtoBigNumberType | null;
   }
diff --git a/ts/textsecure/SendMessage.ts b/ts/textsecure/SendMessage.ts
index 6dc17281dcaf..a6c1f19185a8 100644
--- a/ts/textsecure/SendMessage.ts
+++ b/ts/textsecure/SendMessage.ts
@@ -172,7 +172,6 @@ class Message {
   reaction?: {
     emoji?: string;
     remove?: boolean;
-    targetAuthorE164?: string;
     targetAuthorUuid?: string;
     targetTimestamp?: number;
   };
@@ -315,7 +314,6 @@ class Message {
       proto.reaction = new window.textsecure.protobuf.DataMessage.Reaction();
       proto.reaction.emoji = this.reaction.emoji || null;
       proto.reaction.remove = this.reaction.remove || false;
-      proto.reaction.targetAuthorE164 = this.reaction.targetAuthorE164 || null;
       proto.reaction.targetAuthorUuid = this.reaction.targetAuthorUuid || null;
       proto.reaction.targetTimestamp = this.reaction.targetTimestamp || null;
     }