diff --git a/pdf/out_of_process_instance.cc b/pdf/out_of_process_instance.cc
index 8b9c9f19a3dd..c4d801135053 100644
--- a/pdf/out_of_process_instance.cc
+++ b/pdf/out_of_process_instance.cc
@@ -333,7 +333,9 @@ bool OutOfProcessInstance::Init(uint32_t argc,
   std::string document_url = document_url_var.AsString();
   base::StringPiece document_url_piece(document_url);
   is_print_preview_ = IsPrintPreviewUrl(document_url_piece);
-  if (!document_url_piece.starts_with(kChromeExtension) && !is_print_preview_)
+  if (!document_url_piece.starts_with(kChromeExtension) &&
+      !document_url_piece.starts_with("chrome://pdf-viewer") &&
+      !is_print_preview_)
     return false;
 
   // Check if the plugin is full frame. This is passed in from JS.