diff --git a/DEPS b/DEPS
index b7f717bd2ae5..5d809b9ef490 100644
--- a/DEPS
+++ b/DEPS
@@ -17,7 +17,7 @@ vars = {
   'chromium_version':
     '93.0.4558.0',
   'node_version':
-    'v16.4.0',
+    'v16.4.1',
   'nan_version':
     # The following commit hash of NAN is v2.14.2 with *only* changes to the
     # test suite. This should be updated to a specific tag when one becomes
diff --git a/patches/node/build_add_gn_build_files.patch b/patches/node/build_add_gn_build_files.patch
index 026df763da78..4cdb1b0e7a60 100644
--- a/patches/node/build_add_gn_build_files.patch
+++ b/patches/node/build_add_gn_build_files.patch
@@ -1628,7 +1628,7 @@ index 0000000000000000000000000000000000000000..d1d6b51e8c0c5bc6a5d09e217eb30483
 +  args = rebase_path(inputs + outputs, root_build_dir)
 +}
 diff --git a/src/node_version.h b/src/node_version.h
-index a1a67f0f9034e448a650658df951f160430981ae..c04f70fd1357418b85f1cc64ba9ee0af97076592 100644
+index e4ee8199ca434226f548ddf9f0e4e2770b48df9e..03e59cfeaa32eaba7aeba9be17f986468c34ac6e 100644
 --- a/src/node_version.h
 +++ b/src/node_version.h
 @@ -89,7 +89,10 @@