diff --git a/DEPS b/DEPS
index 110026e134ca..a0ce155d6a56 100644
--- a/DEPS
+++ b/DEPS
@@ -4,7 +4,7 @@ vars = {
   'chromium_version':
     '105.0.5187.0',
   'node_version':
-    'v16.15.1',
+    'v16.16.0',
   'nan_version':
     '16fa32231e2ccd89d2804b3f765319128b20c4ac',
   'squirrel.mac_version':
diff --git a/patches/node/build_add_gn_build_files.patch b/patches/node/build_add_gn_build_files.patch
index 778d72eb5e98..61e2003bd275 100644
--- a/patches/node/build_add_gn_build_files.patch
+++ b/patches/node/build_add_gn_build_files.patch
@@ -1834,7 +1834,7 @@ index 0000000000000000000000000000000000000000..d1d6b51e8c0c5bc6a5d09e217eb30483
 +  args = rebase_path(inputs + outputs, root_build_dir)
 +}
 diff --git a/src/node_version.h b/src/node_version.h
-index 39f6406dd2b52e16a2be5c00c554da30a806ead9..36117c5b36c65f0a8a9bb9c421bc74b82f2b1f3a 100644
+index 0f1a9b52cccba1e54150494a7ee5b28961a8d59d..bb68b2dfef4a693d8a1d0fe056fe696254d12d09 100644
 --- a/src/node_version.h
 +++ b/src/node_version.h
 @@ -89,7 +89,10 @@
diff --git a/patches/node/build_ensure_v8_pointer_compression_sandbox_is_enabled_on_64bit.patch b/patches/node/build_ensure_v8_pointer_compression_sandbox_is_enabled_on_64bit.patch
index 622e1cc6d2de..b21f8958be5d 100644
--- a/patches/node/build_ensure_v8_pointer_compression_sandbox_is_enabled_on_64bit.patch
+++ b/patches/node/build_ensure_v8_pointer_compression_sandbox_is_enabled_on_64bit.patch
@@ -45,10 +45,10 @@ index bdfe81d11cc50f492c93fe48f6946765b6fb5238..ca08deeb19f5fe9ee399ad809b24579f
          'defines': ['V8_31BIT_SMIS_ON_64BIT_ARCH'],
        }],
 diff --git a/configure.py b/configure.py
-index 95b31769cb5756578d66193716c638f504bd44aa..fe741d15da821396883dd72b4e0a42c7758bd557 100755
+index fed2688c792486e5f86509eea0dd6d45f749a99d..426afed7cd0a3a403d4b753af0b25f55024d0f71 100755
 --- a/configure.py
 +++ b/configure.py
-@@ -1433,6 +1433,7 @@ def configure_v8(o):
+@@ -1439,6 +1439,7 @@ def configure_v8(o):
    o['variables']['v8_use_siphash'] = 0 if options.without_siphash else 1
    o['variables']['v8_enable_pointer_compression'] = 1 if options.enable_pointer_compression else 0
    o['variables']['v8_enable_31bit_smis_on_64bit_arch'] = 1 if options.enable_pointer_compression else 0