diff --git a/shell/browser/net/system_network_context_manager.cc b/shell/browser/net/system_network_context_manager.cc
index d1f474d59ead..de3989ad8867 100644
--- a/shell/browser/net/system_network_context_manager.cc
+++ b/shell/browser/net/system_network_context_manager.cc
@@ -288,6 +288,10 @@ void SystemNetworkContextManager::OnNetworkServiceCreated(
       base::FeatureList::IsEnabled(features::kAsyncDns),
       default_secure_dns_mode, doh_config, additional_dns_query_types_enabled);
 
+  // Initializes first party sets component
+  // CL: https://chromium-review.googlesource.com/c/chromium/src/+/3449280
+  content::GetNetworkService()->SetFirstPartySets(base::File());
+
   std::string app_name = electron::Browser::Get()->GetName();
 #if BUILDFLAG(IS_MAC)
   KeychainPassword::GetServiceName() = app_name + " Safe Storage";